Objective: To perform comparative ultrastructural study of parotid glands, submandibular glands, sublingual gland, lacrimal glands, pituitary between minipig and mouse for providing ultrastructural basis for secretary pathway of gene transfer to salivary glands. 研究目的:对比研究小型猪、小鼠的腮腺、颌下腺、舌下腺与泪腺、垂体的超微结构,为涎腺的基因转导治疗蛋白质分泌途径提供超微病理依据。
Among these patients, 12 cases located in parotid glands, 14 in submaxillary glands, 1 in sublingual glands and 48 in minor salivary glands. 腮腺12例,颌下腺14例,舌下腺1例和小涎腺48例。
In addition, the reactivity of DBA and PNA in mucous glands are different, for example, the sublingual and large intestinal glands are negative for DBA and PNA staining. 此外,这些腺体对PNA和DBA的反应也有很大不同,如舌下腺和大肠腺均不与PNA和DBA反应。
After using histochemical method, the epithelial cells of ducts in fetal submandibular, parotid and sublingual glands showed leptin-immunoreactivity weak positive at 13th week. The immunoreactive materials distributed in the epithelial cytoplasm of the ducts. Nuclei were negative. 经免疫组织化学染色,可见13周胎儿下颌下腺、腮腺和舌下腺的导管上皮细胞呈Leptin免疫反应弱阳性,阳性反应产物分布于细胞质中,细胞核呈阴性。